Isky 404A cam - Harley Davidson grind?

[rotorwrench]

The flatheads and sportsters were the only Harleys to use separate cams till the twin cam came out so that must be the pattern they used on that. Nearly all HDs use roller tappets. That type cam would create a lot of side pressure on the tappet no matter what type it is. A person likely would end up sleeving the tappet bores after running that cam for a while.