Hey Pete, have you ever tried any type of flat-top popup piston? Would seem that you'll still get the compression, but open up the roof of the chamber? Obviously, this is what Harley did with the KR - about a 3/16" pop-up. This is what I did with the FlatCad - to mimic the Harley. BUT, I've never had the luxury of time, money and a dyno to try different combinations.
I'd love to have a 1-cylinder engine with a flathead port, head, chamber setup - to test all sorts of things on a motorcycle dyno! LOL
Or maybe cutup a block and make a V-Twin flathead for testing.